翻訳と辞書 Words near each other ・ Mir-575 microRNA precursor family ・ Mir-58 microRNA precursor family ・ Mir-580 microRNA precursor family ・ Mir-584 microRNA precursor family ・ Mir-589 microRNA precursor family ・ Mir-590 microRNA precursor family ・ Mir-592 microRNA precursor family ・ Mir-598 microRNA precursor family ・ Mir-6 microRNA precursor ・ Mir-601 microRNA precursor family ・ Mir-605 microRNA precursor family ・ Mir-61 microRNA precursor family ・ Mir-612 microRNA precursor family ・ Mir-615 microRNA precursor family ・ Mir-616 microRNA precursor family ・ Mir-181 microRNA precursor ・ Mir-184 ・ Mir-185 microRNA precursor family ・ Mir-186 microRNA precursor family ・ Mir-187 microRNA precursor family ・ Mir-188 microRNA precursor family ・ Mir-19 microRNA precursor family ・ Mir-190 microRNA precursor family ・ MiR-191 ・ Mir-192/215 microRNA precursor ・ Mir-193 microRNA precursor family ・ Mir-194 microRNA precursor family ・ Mir-196 microRNA precursor family ・ Mir-198 microRNA precursor family ・ Mir-199 microRNA precursor Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Mir-181 microRNA precursor ： ウィキペディア英語版 Mir-181 microRNA precursor In molecular biology miR-181 microRNA precursor is a small non-coding RNA molecule. MicroRNAs (miRNAs) are transcribed as ~70 nucleotide precursors and subsequently processed by the RNase-III type enzyme Dicer to give a ~22 nucleotide mature product. In this case the mature sequence comes from the 5' arm of the precursor. They target and modulate protein expression by inhibiting translation and / or inducing degradation of target messenger RNAs. This new class of genes has recently been shown to play a central role in malignant transformation. miRNA are downregulated in many tumors and thus appear to function as tumor suppressor genes. The mature products miR-181a, miR-181b, miR-181c or miR-181d are thought to have regulatory roles at posttranscriptional level, through complementarity to target mRNAs. miR-181 which has been predicted or experimentally confirmed in a wide number of vertebrate species as rat, zebrafish, and in the pufferfish (see below) ((MIPF0000007 )). ==Expression== It has been shown that miR-181 is preferentially expressed in the B-lymphoid cells of mouse bone marrow, but also in the retina and brain. In humans, this microRNA is involved in the mechanisms of immunity, and in many different cancers (see below) it was found to be expressed at a particularly low level. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Mir-181 microRNA precursor」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.